resources for HCPs, patients, families and caregivers

Information Is Power

Healthcare professionals, individuals living with rare diseases or disorders, and their supportive networks face a distinct set of challenges. Access to reliable resources is crucial. Below, we have curated a selection of resources for your convenience.

Direct web links are provided where available, but for additional resources, we recommend a search by name in your preferred search engine or visits to established sites within the relevant categories. Always ensure the credibility of the information you find and consult with healthcare professionals for advice tailored to your specific needs.


understanding medical terminolory

Disease, Disorder, Syndrome, Condition: Knowing the Differences

Let's clarify the subtle yet significant distinctions between these commonly used terms to enhance our shared dialogue about health.

Disease

A specific medical issue characterized by a defined set of symptoms and a known cause.

Disorder

A disruption of normal bodily functions manifesting as a group of symptoms, often, but not necessarily, without a pinpointed cause.

Syndrome

A suite of symptoms that frequently occur together, not necessarily with a known cause.

Condition

A broad term that refers to any abnormal state of health, which can encompass diseases, disorders, and syndromes.

Resources

Following is a list of helpful resources to get you started

National Organization for Rare Disorders (NORD)

NORD is a leading advocacy organization for rare diseases. They provide a wealth of information, patient resources, and links to support groups for various rare conditions.  - Website: rarediseases.org (https://rarediseases.org/)

Genetic and Rare Diseases Information Center (GARD)

Run by the National Institutes of Health (NIH), GARD offers a comprehensive database of rare diseases. It includes information on symptoms, causes, and available resources.
Website: rarediseases.info.nih.gov

RareConnect

RareConnect is an online platform that connects patients and families affected by rare diseases worldwide. It offers forums for sharing experiences, support, and resources specific to individual conditions.  - Website: rareconnect.org

Global Genes

Global Genes is a non-profit organization dedicated to advocating for rare diseases. Their website provides educational materials, resources for patients, and links to rare disease communities.
- Website: globalgenes.org

Rare Disease Day

Rare Disease Day is an annual event on the last day of February dedicated to raising awareness about rare diseases. The official website offers resources, stories, and ways to get involved. - Website: rarediseaseday.org

Orphanet

Description: Orphanet is a European database of rare diseases and orphan drugs. It provides information on diagnosis, treatment centers, and ongoing research.  - Website: orphanet.org

PubMed

PubMed is a valuable resource for accessing scientific articles and research papers related to specific rare diseases. It can help patients and caregivers stay informed about the latest developments.  -Website: pubmed.ncbi.nlm.nih.gov

ClinicalTrials

ClinicalTrials.gov is a database providing information on clinical trials for various rare diseases. It can be helpful for patients looking for experimental treatments or research opportunities.  - Website: clinicaltrials.gov

RARE DISEASE SPECIALTIES

Organizations Focused on Specific Rare Diseases

The following organizations focus on specific rare diseases, providing vital support, resources, and advocacy for individuals and families dealing with these conditions. Please note that this is not an exhaustive list, and there are many more organizations dedicated to rare diseases.

Cystic Fibrosis Foundation

- Rare Disease: Cystic Fibrosis  
The Cystic Fibrosis Foundation is dedicated to finding a cure and improving the lives of those with cystic fibrosis, a genetic lung disorder.

ALS Association

- Rare Disease: Amyotrophic Lateral Sclerosis (ALS)  
The ALS Association focuses on supporting and advocating for individuals with ALS, a rare neurodegenerative disease.

Marfan Foundation

- Rare Disease: Marfan Syndrome  
The Marfan Foundation provides resources and support to individuals and families affected by Marfan syndrome and related connective tissue disorders.

NephCure Kidney International

- Rare Disease: Nephrotic Syndrome NephCure Kidney International is dedicated to finding better treatments and a cure for Nephrotic Syndrome and other kidney diseases.

Tuberous Sclerosis Alliance

- Rare Disease: Tuberous Sclerosis Complex (TSC)
The Tuberous Sclerosis Alliance supports individuals and families affected by TSC, a genetic disorder that causes noncancerous tumors to form in many organs.

Histiocytosis Association

- Rare Disease: Langerhans Cell Histiocytosis (LCH) and other histiocytic disorders  
The Histiocytosis Association provides information and support for those affected by LCH and related histiocytic disorders.

Alport Syndrome Foundation

- Rare Disease: Alport Syndrome  
The Alport Syndrome Foundation is dedicated to improving the lives of those with Alport Syndrome, a rare genetic kidney disease.

Ectodermal Dysplasia Society

- Rare Disease: Ectodermal Dysplasia  
The Ectodermal Dysplasia Society offers support and resources for individuals with ectodermal dysplasia, a group of rare genetic conditions affecting the skin, hair, teeth, and more.

FOP Connection

- Rare Disease: Fibrodysplasia Ossificans Progressiva (FOP)  
FOP Connection is a support network for individuals and families living with FOP, an extremely rare condition where soft tissues progressively turn into bone.

Batten Disease Support and Research Association (BDSRA)

- Rare Disease: Batten Disease    
BDSRA provides support, information, and advocacy for families affected by Batten Disease, a group of rare neurological disorders.

World Federation of Hemophilia (WFH)

WFH is a global organization dedicated to improving the lives of people with hemophilia and other bleeding disorders. They provide information, support, and resources for patients and families.  - Website: wfhemophilia.org

National Hemophilia Foundation (NHF)

NHF is a leading patient advocacy organization in the United States that focuses on bleeding disorders, including hemophilia and rare clotting disorders. They offer educational materials and support.  - Website: hemophilia.org

European Haemophilia Consortium (EHC)

EHC is an umbrella organization for patient groups in Europe that represent individuals with hemophilia and other bleeding disorders. They provide resources and support for patients.  - Website: ehc.eu

Hemostasis and Thrombosis Center (HTC) Network

Many countries have HTC networks that specialize in the treatment and care of individuals with bleeding and clotting disorders. These centers provide expert care and support.  - Website: Search for your local HTC network.

Clotting Disorders Patient Advocacy

Some clotting disorders have dedicated patient advocacy organizations. For example, the National Blood Clot Alliance (NBCA) in the United States focuses on clotting disorders.  - Website: stoptheclot.org

Initiatives & programs

Pharmaceutical Companies with Rare Disease Patient Initiatives and Programs

Novartis

Novartis has various patient support programs and collaborates with patient advocacy organizations to improve the lives of rare disease patients. They are involved in research and development for rare diseases.

Sanofi Genzyme

Sanofi Genzyme is dedicated to rare diseases and offers patient support programs, educational resources, and advocacy efforts. They have a strong focus on enzyme replacement therapies.

Takeda (formerly Shire)

Takeda is known for its commitment to rare diseases. They have patient support programs, educational resources, and partnerships with rare disease advocacy groups.

Bristol-Myers Squibb

Bristol-Myers Squibb is involved in rare disease research and has initiatives to support patients with rare diseases. They collaborate with patient organizations.

Vertex Pharmaceuticals

Vertex is focused on cystic fibrosis and has patient support programs, including financial assistance and educational resources.

Amicus Therapeutics

Amicus Therapeutics is dedicated to rare metabolic disorders. They offer patient support programs and resources for individuals and families affected by rare diseases.

BioMarin Pharmaceutical

BioMarin focuses on rare genetic diseases. They have patient advocacy efforts, patient support programs, and educational resources.

AstraZeneca (including Alexion Pharmaceuticals)

AstraZeneca, including Alexion Pharmaceuticals, is involved in rare disease research and offers patient support programs and resources for rare disease patients.

Ultragenyx Pharmaceutical

Ultragenyx is dedicated to rare metabolic diseases and offers patient support programs and resources for patients and caregivers.

Regeneron Pharmaceuticals

Regeneron is involved in rare disease research and collaborates with patient advocacy organizations to support rare disease patients.

Advocacy Groups

Rare Diseases Policy Advocacy Groups

These organizations and groups focus on advocating for policies that benefit patients with rare diseases, raising awareness, and providing support and resources. Please visit their respective websites for more information on their policy initiatives and advocacy efforts.

The EveryLife Foundation for Rare Diseases

This foundation works to accelerate biotech innovation for rare disease treatments. They advocate for policies that support rare disease research and therapies.  - Website: everylifefoundation.org

Rare Disease Legislative Advocates (RDLA)

RDLA is a program of the EveryLife Foundation for Rare Diseases. They advocate for federal legislation and policies that benefit rare disease patients in the United States.  - Website: everylifefoundation.org/rdla

National Organization for Rare Disorders (NORD)

NORD is a leading advocacy organization for rare diseases. They work on policy issues related to rare diseases in the United States and provide support for patients and families.  - Website: rarediseases.org

Global Genes

Global Genes works on policy initiatives and provide resources for patients with rare diseases worldwide  - Website: globalgenes.org

EURORDIS - Rare Diseases Europe

EURORDIS is a European alliance of rare disease patient organizations. The advocate for rare disease policies and support patients' rights in Europe.  - Website: eurordis.org

Rare Diseases International (RDI)

RDI is a global alliance of rare disease patient organizations. They work on global policy issues related to rare diseases.  - Website: rarediseasesinternational.org

Rare Disease UK (RDUK)

RDUK is a campaign for rare disease patients in the United Kingdom. They advocate for improved policies and support for rare diseases in the UK.  - Website: raredisease.org.uk